Flwo cytometric DNA content analysis was performed on 41 paraffin embedded archival specimens obtained from patients with endometrial carcinoma who had been surgically treated duration in Cheil general hospital. We evaluated the relationships
between
the surgical stage (FIGO,1989), histological tumor grade, myometrial invasion, vascular invasion, histologic type and DNA ploidy determined by flow cytometry. Diploid DNA patterns were identified in 30 (72.3%0 specimens and aneuploidy were
observed
in
remaining 11(26.8%). The incidences of aneuploidy were significantly increased with the stage (P<0.01), and tended to be more frequently founded in association with deeper myometrial invasion, higher histologic tumor grade, positive vascular
invasion,
poorer histologic type. These results suggested that the prognosis of endometrial cancer can be precisely predicted by DNA ploidy pattern with other pathological prognostic factors.
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